英文名称:Albumin
中文名称:白蛋白抗体
别    名:Alb 1; ALB; ALBU_MOUSE; Albumin 1; Mouse serum albumin; DKFZp779N1935; PRO0883; PRO0903; PRO1341; PRO2044; PRO2619; Serum albumin.  
研究领域:肿瘤  细胞生物  免疫学  发育生物学  干细胞  新陈代谢  
抗体来源:Rabbit
克隆类型:Polyclonal
交叉反应: Human, Mouse, 
产品应用:WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量:68kDa
细胞定位:分泌型蛋白 
性    状:Liquid
浓    度:1mg/ml
免 疫 原:Mouse serum albumin purified from mouse serum: full length 
亚    型:IgG
纯化方法:affinity purified by Protein A
缓 冲 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMedPubMed
产品介绍 Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. [provided by RefSeq, Jul 2008].

Function:
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.

Subcellular Location:
Secreted.

Tissue Specificity:
Plasma.

Post-translational modifications:
Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606. 
Glycated in diabetic patients. 
Phosphorylation sites are present in the extracellular medium. 
Acetylated on Lys-223 by acetylsalicylic acid.

DISEASE:
Familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]: Form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the ALB/AFP/VDB family.
Contains 3 albumin domains.

SWISS:
P02769

Gene ID:
280717

Database links:
Entrez Gene: 100379232 Guinea pig
Entrez Gene: 100034206 Horse
Entrez Gene: 213 Human
Entrez Gene: 11657 Mouse
Entrez Gene: 396960 Pig
Entrez Gene: 100009195 Rabbit
Entrez Gene: 24186 Rat
Omim: 103600 Human
SwissProt: P49064 Cat
SwissProt: P19121 Chicken
SwissProt: P02769 Cow
SwissProt: P49822 Dog
SwissProt: P35747 Horse
SwissProt: P02768 Human
SwissProt: P07724 Mouse
SwissProt: P08835 Pig
SwissProt: P49065 Rabbit
SwissProt: P02770 Rat
Unigene: 418167 Human
Unigene: 16773 Mouse
Unigene: 202968 Rat