英文名称:Human CEA
中文名称:癌胚抗原单克隆抗体
别    名:Carcinoembryonic antigen; Carcinoembryonic antigen related cell adhesion molecule 5; Carcinoembryonic antigen-related cell adhesion molecule 5; CD66e; CD66e; CD66e antigen; CEACAM5; CEAM5_HUMAN; DKFZp781M2392; Meconium antigen 100.  
研究领域肿瘤  免疫学  干细胞  肿瘤细胞生物标志物  
抗体来源:Mouse
克隆类型:Monoclonal
克 隆 号:9G8
交叉反应: (predicted: Human, )
产品应用:ELISA=1:5000-10000  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量:71kDa
细胞定位:细胞膜 
性    状:Liquid
免 疫 原:Recombinant Human CEACAM5 Protein: 35-685/702 
亚    型;IgG1
纯化方法:affinity purified by Protein A
缓 冲 液:0.01M PBS(pH7.4)
保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMedPubMed
产品介绍CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) and 11 pregnancy-specific glyco-protein (PSG 1-PSG 11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/ CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.

SWISS:
P40199

Gene ID:
4680